Marcelle Ferron was born at Louiseville in 1924. She studied at the École des Beaux-Arts de Québec until 1944.

In 1948, she was a co-signer of "Refus Global" manifesto with Paul-Émile Borduas, Jean-Paul Riopelle and some others. She gets her first solo exhibition at Librairie Tranquille, Montreal, in 1949. Ferron participated in all the Automatiste group exhibitions, including the critically acclaimed retrospective, Borduas et les Automatistes at the Grand Palais in Paris in 1971. Her work was exhibited in numerous collective exhibitions, both in Europe and the U.S., including: L'Exposition des Surindépendants and le Salon des Réalités nouvelles in 1956, the Antagonisme show at the Louvre in 1960, and at the Paris Musée d'art moderne in 1962 and 1965. She also represented Quebec at the Sao Paulo Biennial in 1961, the Festival des Deux Mondes in Spoleto in 1962, and the Osaka Universal Exposition in 1970. Her works have been the subject of more than thirty special shows throughout Quebec and Canada, as well as in Paris, Brussels and Munich. In 1970, the Musée d'art contemporain de Montréal staged a retrospective of her work, a show that was repeated in 1972 in Paris at the Canadian Cultural Centre.

1953, she moved to Paris, where she worked prodigiously for thirteen years producing drawings and paintings and, at the same time, initiating herself into the art of the master glassworker. Marcelle Ferron has been working with modern stained glass concepts since 1964. Examples of her work can be admired in the Champ-de-Mars and Vendôme métro stations and the International Aviation Building, all in Montreal, as well as at Place du Portage in Hull and the Court House in Granby. An associate professor at Laval University in Quebec, Ferron has participated in numerous seminars and given many conferences throughout Europe and America.